How much is a flight from Santo Domingo to Mayaguez?

There’s no fixed price — fares between Santo Domingo and Mayaguez can vary a lot by day or time.

Pick a travel date to see today’s available fares.

Flying during the week can be more affordable, as weekend flights tend to be pricier. Also consider demand and availability: the last remaining seats often come at higher fares!

Best airport options between Santo Domingo and Mayaguez

If you're open to flying into or out of more than one airport, you’ll have more routes to compare.

• Airports in Santo Domingo: An alternative to Santo Domingo - Las Américas is La Isabela.
• Airports in Mayaguez: Mayaguez - Eugenio Maria de Hostos is the sole airport currently available.

Some airports offer extras like lounges, fast track, or self check-in — good to keep in mind. Comparing airports by services offered helps you balance cost and comfort.

Compare flights from Santo Domingo to Mayaguez with advanced filters

Find your ideal flight using Jetcost. Select whether you want nonstop or connecting flights, round-trip or one-way, and filter by airline, price, or booking site.

Other popular destinations

Looking for alternatives in Puerto Rico? Travelers also liked: Aguadilla, Culebra Airport, Ponce, San Juan, Vieques Airport.

If you have a preferred time to leave or arrive, filters can help you show only the matching flights. You can also filter by your favorite airline and see only those deals.