Flight prices from Southampton to Mytilene

There’s no fixed price — fares between Southampton and Mytilene can vary a lot by day or time.

Choose a date to explore the best fares now.

The lowest fares are often found with some flexibility in travel dates. If your plans are flexible, you’ll have a better chance of finding cheap flights.

Planning flights between Southampton and Mytilene? Don’t forget the airport options

Especially when flying to medium or large cities, it's worth checking all possible airport combinations before booking.

• Airports in Southampton: Southampton is the only airport in this city.
• Airports in Mytilene: Only Mytilene is currently available.

Check for differences in transport costs to and from each airport — they affect your total spend. Choosing the right airport can make a real difference in price and timing.

Adjust your flight filters for Southampton – Mytilene

Jetcost gives you tools to search smarter. Pick your ideal price range, airline, departure time, and flight type — then compare offers from the best travel agencies and carriers.

Other popular destinations

Planning a trip to Greece? These cities are popular too: Athens, Crete, Kerkyra, Thessaloniki, Thira.

Sorting options let you see the most affordable flights first. Some results may include extra fees shown only at checkout — always read carefully to see what’s included.